A small fraction of cancers can arise in a family context. For some of these families, the genetic cause can be determined.
The national guidelines were developed for some of these hereditary syndromes. They include the phenotype of the familial cancer as well as other characteristics and the genes to be tested.
The genetic tests enable screening and prevention and have recently been found to have therapeutic benefits.
All of the genes concerned were validated (in terms of risk) at the time of publication of these guidelines. Since their publication, the eligibility criteria for the tests and the list of genes have been extended.
In the case of breast and ovarian cancer, some experts recommend screening everyone who requests it, although others still adhere to the national guidelines. The list of test genes has grown significantly.
The data contained in these guidelines must therefore be seen as minimum criteria.
They are intended for medical staff for preventive, diagnostic or therapeutic purposes.
Oncogenetic tests sheets
Hereditary endocrine cancers
Skin cancer syndromes
- Birt-Hogg-Dubé syndrome
- Familial atypical multiple mole melanoma
- Neurofibromatosis type 1
- Neurofibromatosis type 2
Hereditary forms of breast and ovarian cancer
Li-Fraumeni and Cowden Syndromes